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alanine.html
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<!-- This codebase desgin according to mozilla open source license.
Redistribution , contribution and improve codebase under license
convensions. @contact Ali Hassan AliMatrixCode@protonmail.com -->
<!DOCTYPE html>
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<div class="card-header"> Alanine </div>
<div class="card-body">
<h5 class="card-title"> <i class="fa fa-info-circle" aria-hidden="true" title="information about amino-acid"></i>
</h5>
<p class="card-text">
<a-scene>
<a-assets>
<a-asset-item id="Alanine_Aminotransferase" src="/models/3IHJ.glb"></a-asset-item>
</a-assets>
<a-entity gltf-model="#Alanine_Aminotransferase" animation-mixer position="30 44 -150" rotation="100 0 20"></a-entity>
</a-scene>
<table>
<tr>
<th> Group, </th>
<th> Alien-Protein-code, </th>
<th> Agent, </th>
<th> Formula, </th>
</tr>
<tr>
<td> Amine group & carboxylic acid group, </td>
<td> ALT </td>
<td> Neutral, </td>
<td>
<a class="jmol" href="https://chemapps.stolaf.edu/jmol/jmol.php?model=C%5BC%40%40H%5D%28C%28%3DO%29%5BO-%5D%29%5BNH3%2B%5D" title="Chemical structure of alanine molecule. Alanine belong to Methyl group. In Alanine compound Hydrogen atoms are abudant.">
C<small class="subscript">3-</small>H<small class="subscript">7-</small>NO<small class="subscript">2</small>
</a>
</td>
</tr>
<tr>
<th> Weight, </th>
<th> Nature, </th>
<th> Role, </th>
<th> Sidechain, </th>
</tr>
<tr>
<td>
89.094 g·mol−1,
</td>
<td>
Non-polar & Aliphatic,
</td>
<td>
The L-isomer of alanine (left-handed) is the one that is incorporated into proteins.
The right-handed form, D-alanine, occurs in polypeptides in some bacterial cell walls and in some peptide antibiotics, and occurs in the tissues of many crustaceans and molluscs as an osmolyte.
Alanine is also very abundant (over-represented) in low complexity regions of proteins.
Alanine can be synthesized from pyruvate and branched chain amino acids such as valine, leucine, and isoleucine.
In mammals, alanine plays a key role in glucose–alanine cycle between tissues and liver.
The alanine enters the bloodstream, and is transported to the liver.
Glutamate in the liver enters mitochondria and is broken down by glutamate dehydrogenase into α-ketoglutarate and ammonium, which in turn participates in the urea cycle to form urea which is excreted through the kidneys.
Alterations in the alanine cycle that increase the levels of serum alanine aminotransferase (ALT) are linked to the development of type II diabetes.
</td>
<td>
Methyl group,
</td>
</tr>
</table>
</p>
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