diff --git a/.changeset/get-dependencies-from-esm-without-main.md b/.changeset/get-dependencies-from-esm-without-main.md
new file mode 100644
index 00000000000..614a898bea6
--- /dev/null
+++ b/.changeset/get-dependencies-from-esm-without-main.md
@@ -0,0 +1,5 @@
+---
+"@remix-run/dev": patch
+---
+
+Update `getDependenciesToBundle` to handle ESM packages without main exports. Note that these packages must expose `package.json` in their `exports` field so that their path can be resolved.
diff --git a/integration/compiler-test.ts b/integration/compiler-test.ts
index 116e94abde7..12cbe904c37 100644
--- a/integration/compiler-test.ts
+++ b/integration/compiler-test.ts
@@ -28,6 +28,7 @@ test.describe("compiler", () => {
               "esm-only-pkg",
               "esm-only-single-export",
               ...getDependenciesToBundle("esm-only-exports-pkg"),
+              ...getDependenciesToBundle("esm-only-nested-exports-pkg"),
             ],
           };
         `,
@@ -84,6 +85,13 @@ test.describe("compiler", () => {
             return <div id="esm-only-exports-pkg">{esmOnlyPkg}</div>;
           }
         `,
+        "app/routes/esm-only-nested-exports-pkg.tsx": js`
+          import esmOnlyPkg from "esm-only-nested-exports-pkg/nested";
+
+          export default function EsmOnlyPkg() {
+            return <div id="esm-only-nested-exports-pkg">{esmOnlyPkg}</div>;
+          }
+        `,
         "app/routes/esm-only-single-export.tsx": js`
           import esmOnlyPkg from "esm-only-single-export";
 
@@ -129,6 +137,18 @@ test.describe("compiler", () => {
         "node_modules/esm-only-exports-pkg/esm-only-exports-pkg.js": js`
           export default "esm-only-exports-pkg";
         `,
+        "node_modules/esm-only-nested-exports-pkg/package.json": json({
+          name: "esm-only-nested-exports-pkg",
+          version: "1.0.0",
+          type: "module",
+          exports: {
+            "./package.json": "./package.json",
+            "./nested": "./esm-only-nested-exports-pkg.js",
+          },
+        }),
+        "node_modules/esm-only-nested-exports-pkg/esm-only-nested-exports-pkg.js": js`
+          export default "esm-only-nested-exports-pkg";
+        `,
         "node_modules/esm-only-single-export/package.json": json({
           name: "esm-only-exports-pkg",
           version: "1.0.0",
@@ -288,6 +308,18 @@ test.describe("compiler", () => {
     );
   });
 
+  test("allows consumption of ESM modules with only nested exports in CJS builds with `serverDependenciesToBundle` and `getDependenciesToBundle`", async ({
+    page,
+  }) => {
+    let app = new PlaywrightFixture(appFixture, page);
+    let res = await app.goto("/esm-only-nested-exports-pkg", true);
+    expect(res.status()).toBe(200); // server rendered fine
+    // rendered the page instead of the error boundary
+    expect(await app.getHtml("#esm-only-nested-exports-pkg")).toBe(
+      '<div id="esm-only-nested-exports-pkg">esm-only-nested-exports-pkg</div>'
+    );
+  });
+
   test("allows consumption of packages with sub modules", async ({ page }) => {
     let app = new PlaywrightFixture(appFixture, page);
     let res = await app.goto("/package-with-submodule", true);
diff --git a/packages/remix-dev/dependencies.ts b/packages/remix-dev/dependencies.ts
index cbf53c10781..e3d6393aab8 100644
--- a/packages/remix-dev/dependencies.ts
+++ b/packages/remix-dev/dependencies.ts
@@ -40,6 +40,17 @@ export function getDependenciesToBundle(...pkg: string[]): string[] {
   return Array.from(aggregatedDeps);
 }
 
+interface ErrorWithCode extends Error {
+  code: string;
+}
+
+function isErrorWithCode(error: unknown): error is ErrorWithCode {
+  return (
+    error instanceof Error &&
+    typeof (error as NodeJS.ErrnoException).code === "string"
+  );
+}
+
 function getPackageDependenciesRecursive(
   pkg: string,
   aggregatedDeps: Set<string>,
@@ -47,7 +58,18 @@ function getPackageDependenciesRecursive(
 ): void {
   visitedPackages.add(pkg);
 
-  let pkgPath = require.resolve(pkg);
+  let pkgPath: string;
+  try {
+    pkgPath = require.resolve(pkg);
+  } catch (err) {
+    if (isErrorWithCode(err) && err.code === "ERR_PACKAGE_PATH_NOT_EXPORTED") {
+      // Handle packages without main exports.
+      // They at least need to have package.json exported.
+      pkgPath = require.resolve(`${pkg}/package.json`);
+    } else {
+      throw err;
+    }
+  }
   let lastIndexOfPackageName = pkgPath.lastIndexOf(pkg);
   if (lastIndexOfPackageName !== -1) {
     pkgPath = pkgPath.substring(0, lastIndexOfPackageName);