Opium poppy (Papaver somniferum L.) is one of the oldest and most important medicinal plants worldwide, producing several pharmaceutically important benzylisoquinoline alkaloids (BIAs) within a tissue specific pattern, including noscapine, morphine, and codeine. With relatively complete studies on genome, transcriptome and biochemical metabolism for P. somniferum, the regulatory mechanisms within epigenomic levels behind active ingredients production as well as tissue specific pattern construction remains unknown. Here, we performed comprehensive RNA sequencing (RNA-seq) and assay for transposase-accessible chromatin sequencing (ATAC-seq) across six distinctive tissues (capsule, stem, fine root, tap root, leaf, and petal) in P. somniferum. Using these data, we wanted to address the main topic: delineate the cis-regulatory motifs and transcription factors that regulate tissue-specific BIA metabolism.
If you have any questions, please contact with Yu Xu (stu.yuxu@gmail.com) or Kai Ye (kaiye@xjtu.edu.cn).
Jia Y, Xu Y, Wang B, Guo L, Guo M, Che X and Ye K (2023) The tissue-specific chromatin accessibility landscape of Papaver somniferum. Front. Genet. 14:1136736. doi: 10.3389/fgene.2023.1136736